Common Side Effects: Amelia and Wyatt (Adult Swim, Sunday, March 16, 2025)

Common Side Affects Key Art

Adult Swim’s “Common Side Effects” continues its trippy first season this Sunday, and things are about to get weird. No, really weird. This is a show, after all, about former high school lab partners who accidentally stumble upon a potential cure for every disease known to humanity – a cure involving rare mushrooms, naturally.

In “Amelia and Wyatt,” the eighth episode of the season, Marshall finds himself at a crossroads, a shift in circumstance that forces him to reach out to an old acquaintance and re-evaluate his entire plan. Meanwhile, Frances is reeling from some unsettling news, leaving her in a state of emotional disarray.

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The overarching storyline of “Common Side Effects” revolves around a conspiracy involving big pharma and the aforementioned miracle mushroom. The show has a darkly comedic way of tackling serious subjects, skewering corporate greed and societal anxieties with sharp wit and surreal animation.

If you’re looking for a show that embraces the strange and asks big questions while keeping you entertained, “Common Side Effects” might just be the cure for your TV boredom. Catch “Amelia and Wyatt” this Sunday, March 16th at 11:30 PM ET on Adult Swim.

Andrew Martins, reviewer, recapper, deep diver, scifi specialist. Thinks Blakes 7 is better than Star Trek. Yes I do go to fan conventions and no I don't dress up. Well okay maybe I do a bit.